OLYMPUS DIGITAL CAMERAProf. Tomáš Adam, Ph.D.
Head manager of Laboratory of Metabolomics and Department of Clinical Biochemistry, tomasadam@gmail.com, +420 588 444 231
David FriedeckyDavid Friedecký, Ph.D.
Head of the Instrumental Methods section, david.friedecky@gmail.com, +420 588 442 619
David is responsible for LC/MS methods in diagnostic laboratory (newborn screening, therapeutic drug monitoring and method for diagnosing of IMDs). The main research focus cover metabolomics, drug metabolisation, flow injection analysis coupled with mass spectrometry and other fields of mass spectrometry in clinical research.
Micova - foto 2Kateřina Mičová, Ph.D.
Mass spectrometry specialist
katerinamicova@gmail.com; +420 588 442 619ochemistry of this disorders.
Hana JaneckovaHana Janečková, Ph.D.
janeckovah@gmail.com; +420 588 443 234

Ph.D. students


Lukáš Najdekr
Lukáš is involved mainly in untargeted metabolomics and statistics using R programming language. Focus in analytical chemistry is in the field of high-resolution accurate-mass (HRAM) mass spectrometry coupled with liquid chromatography, specializing on the Orbitrap technology. He finished his master degree in Biochemistry and his doing his Ph.D. on Medical Genetics. Merging the knowledge of programming, analytical chemistry and biochemistry allows him, among other things, to cooperate on testing of new software developed by companies such as HighChem and Thermo Fisher Scientific.
student - Vrobel IvoIvo Vrobel
Ivo is evaluating the effect of chosen drugs (anti-cancer, anti-platelet) on human metabolome using LC-MS targeted and untargeted pharmacometabolomic approach. The goal is to find biomarkers, which could predict which patients will respond to therapy or which patients are at higher risk of developing adverse effects. I am also involved in developing new LC-MS analytical methods for therapeutic drug monitoring.
student - Karlikova RadanaRadana Karlíková
Ráďa is interested in metabolic disorders, biochemical parthways and metabolomics. I focus on targeted and untargeted metabolomic of perinatal asphyxia and chronic myeloid leukemia The main goal is the identification of biomarkers and understanding changes in metablolic pathways important for patobiochemistry of this disorders.
studenti - Gardlo AlzbetaAlžběta Gardlo
Bětka is studying the possibility of using advanced multivariate statistical methods for statistical analysis of metabolomical data, including the use of appropriate software tools (especially software R). The main part of the thesis is the application of the methodology of logratio analysis of compositional data.
studenti - Jacova SlavkaJaroslava Jáčová
Slávka is interested in metabolomic analysis of biofluids, especially urine. The main analytical tool she uses is comprehensive two-dimensional gas chromatography coupled with mass spectrometry (GC×GC/TOF-MS). She focuses on utilization of high separation efficiency of this technique to trace analysis and identification of new biomarkers of metabolic disorders.
student - Vaclavik JanJan Václavík
Jenda is interested in evaluation of diagnostic performance of high-performance liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS) and tandem mass spectrometry (LC-MS/MS) for identification of biomarkers of purine and pyrimidine metabolic disorders and he works on LC-MS method development.